Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13530275 | 0.86 | MAPT (0.44) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13529288 | 0.86 | ALDH1A1 (0.43) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13530331 | 0.85 | ALDH1A1 (0.47) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13530127 | 0.78 | ALDH1A1 (0.41) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13529386 | 0.78 | ALDH1A1 (0.38) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL17004446 | 0.78 | CYP1A2 (0.36) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL17004447 | 0.78 | CYP1A2 (0.36) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13530474 | 0.78 | ESR1 (0.42) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13529500 | 0.78 | CYP1A2 (0.38) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13530020 | 0.77 | RAB9A (0.38) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009094442-A2 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-07-30 | — | — | WO | disclosed |