Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13783475 | 0.89 | MAPT (0.40) | MEN1KMT2AMAPK1CYP2C9GBA1 | |
| Hydrochloric Acid SCHEMBL2922661 | 0.88 | ELANE (0.43) | MEN1KMT2AMAPK1HTR6CYP2C9 | |
| SCHEMBL13765376 | 0.83 | SMN1; SMN2 (0.46) | MEN1KMT2AMAPK1HTR6KDM4E | |
| SCHEMBL12392496 | 0.82 | NOD2 (0.48) | MEN1KMT2AHTR6MAPTKDM4E | |
| SCHEMBL13765391 | 0.81 | ALDH1A1 (0.43) | MEN1KMT2AMAPK1GBA1MAPT | |
| SCHEMBL13765387 | 0.80 | NOD2 (0.46) | MEN1KMT2AHTR6CYP2C9MAPT | |
| SCHEMBL2929041 | 0.78 | SMN1; SMN2 (0.47) | MEN1KMT2AMAPK1MAPTKDM4E | |
| SCHEMBL2928016 | 0.78 | KMT2A (0.47) | MEN1KMT2AMAPK1MAPTKDM4E | |
| SCHEMBL12229940 | 0.77 | NOD2 (0.49) | MEN1KMT2AHTR6MAPTKDM4E | |
| SCHEMBL2924410 | 0.76 | ALDH1A1 (0.45) | MEN1KMT2AHTR6CYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560546-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-07-14 | — | — | US | disclosed |