Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16318225 | 0.81 | ALDH1A1 (0.33) | ALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL13765456 | 0.81 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| SCHEMBL16318255 | 0.79 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL13769708 | 0.77 | MEN1 (0.31) | ALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL13765460 | 0.75 | MEN1 (0.32) | ALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL11965871 | 0.74 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| SCHEMBL9626733 | 0.74 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| SCHEMBL13130096 | 0.72 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL10150744 | 0.69 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| SCHEMBL739795 | 0.68 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176732-A1 | PROTECTED NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA INC. (US) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176732-A1 | PROTECTED NUCLEOTIDE ANALOGS | NTPCR, NT5C2, PNP | ALDH1A1 941/4885LMNA 777/4885HSD17B10 4243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.