Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.38 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Cresol SCHEMBL28372655 | 0.81 | ACHE (0.77) | ACHETDP1ALDH1A1CA2CA1 | |
| P-Xylene SCHEMBL15210153 | 0.78 | ACHE (0.44) | ACHETDP1ALDH1A1CA2CA1 | |
| P-Xylene SCHEMBL15210189 | 0.78 | ACHE (0.44) | ACHETDP1ALDH1A1CA2CA1 | |
| P-Xylene SCHEMBL11772917 | 0.78 | ACHE (1.00) | ACHETDP1ALDH1A1CA2CA1 | |
| P-Xylene SCHEMBL771 | 0.78 | — | — | |
| P-Xylene SCHEMBL11770184 | 0.78 | ACHE (1.00) | ACHETDP1ALDH1A1CA2CA1 | |
| P-Xylene SCHEMBL460348 | 0.78 | ACHE (1.00) | ACHETDP1ALDH1A1CA2CA1 | |
| P-Cresol SCHEMBL216516 | 0.74 | ACHE (0.65) | ACHETDP1ALDH1A1CA2CA1 | |
| P-Xylene SCHEMBL180004 | 0.74 | ACHE (0.89) | ACHETDP1ALDH1A1CA2CA1 | |
| P-Xylene SCHEMBL11003481 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191490-A1 | PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF | Medimmune Limited (GB) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016038383-A1 | PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF | MEDIMMUNE LIMITED (GB) | 2016-03-17 | — | — | WO | disclosed |
| EP-2968596-A2 | PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF | MEDIMMUNE LIMITED (GB) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014159981-A2 | PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF | SPIROGEN SARL (CH) | 2014-10-02 | — | — | WO | disclosed |
| US-20110275810-A1 | CARBAMIC ACID COMPOUNDS COMPRISING A PIPERAZINE LINKAGE AS HDAC INHIBITORS | TOPOTARGET UK LIMITED (GB) | 2011-11-10 | — | — | US | disclosed |
| US-4404361-A | BISIMIDE CONTAINING HALOGEN ATOMS AND AMMONIUM ACID TETRAHALOPHTHALATE | SAYTECH, INC. (US) | 1983-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275810-A1 | CARBAMIC ACID COMPOUNDS COMPRISING A PIPERAZINE LINKAGE AS HDAC INHIBITORS | HDAC5, HDAC1, HDAC7 | ACHE 3385/4885TDP1 2679/4885ALDH1A1 1221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.