P-Xylene

P-Xylene

SCHEMBL460348

Cc1ccc(C)cc1.Cc1ccc(C)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 1.00
TDP1 Q9NUW8 1/20 1.00
ALDH1A1 P00352 4/20 0.61
CA2 P00918 2/20 0.61
CA1 P00915 1/20 0.61
CA7 P43166 1/20 0.61
CA9 Q16790 1/20 0.61
TSHR P16473 3/20 0.58
LMNA P02545 2/20 0.58
ALOX12 P18054 1/20 0.58
CYP2A6 P11509 3/20 0.50
IDO1 P14902 1/20 0.50
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
LPL P06858 1/20 0.50
LIPG Q9Y5X9 1/20 0.50
CYP1A2 P05177 1/20 0.50
ORAI1 Q96D31 1/20 0.50
ORAI2 Q96SN7 1/20 0.50
ORAI3 Q9BRQ5 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xylene SCHEMBL11770184 1.00 ACHE (1.00) ACHETDP1ALDH1A1CA2CA1
P-Xylene SCHEMBL11772917 1.00 ACHE (1.00) ACHETDP1ALDH1A1CA2CA1
P-Xylene SCHEMBL771 1.00
P-Xylene SCHEMBL3847044 0.94
P-Xylene SCHEMBL461064 0.94 ACHE (0.89) ACHETDP1ALDH1A1CA2CA1
P-Xylene SCHEMBL11003481 0.94
P-Xylene SCHEMBL9119408 0.94 ACHE (0.89) ACHETDP1ALDH1A1CA2CA1
P-Xylene SCHEMBL20873607 0.94
P-Xylene SCHEMBL21270023 0.94
P-Xylene SCHEMBL1508153 0.94 ACHE (0.89) ACHETDP1ALDH1A1CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111259543-B Design method of SVE process parameters in petroleum pollution sites 生态环境部土壤与农业农村生态环境监管技术中心 2024-01-23 CN disclosed
CN-112763642-A High performance liquid detection method for benzene pollutants in water body 中国石油天然气集团有限公司 2021-05-07 CN disclosed
CN-111259543-A Design method of SVE (singular value analysis) process parameters in petroleum-polluted site 生态环境部土壤与农业农村生态环境监管技术中心 2020-06-09 CN disclosed
US-20200171214-A1 BIORESORBABLE SURFACE COATING FOR DELAYING DEGRADATION DREI LILIEN PVG GMBH & CO. KG (DE) 2020-06-04 US disclosed
US-10626256-B2 Solution polymerization process NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2020-04-21 US disclosed
CN-110172461-A A kind of construction method of novel osteosarcoma Lung metastases model and its application 上海长征医院 2019-08-27 CN disclosed
CN-109999899-A It is a kind of for the EU-1 molecular sieve catalyst of methylbenzene shape selective disproportionation and its application 西安元创化工科技股份有限公司 2019-07-12 CN disclosed
CN-108290110-A The separation of mixed xylenes 埃克森美孚研究工程公司 2018-07-17 CN disclosed
US-10000630-B2 Ethylene interpolymers having improved color NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2018-06-19 US disclosed
CN-105246864-B Method for purifying 1, 3-butadiene from an oxidative dehydrogenation process 环球油品公司 2018-03-23 CN disclosed
US-8049029-B2 Process for preparing 2-amino-5-cyanobenzoic acid derivatives E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-01 US disclosed
US-7972551-B2 Method of producing solid body having depressed portions on its surface and method of producing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2011-07-05 US disclosed
US-20100075246-A1 METHOD OF PRODUCING SOLID BODY HAVING DEPRESSED PORTIONS ON ITS SURFACE AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2010-03-25 US disclosed
WO-2008100733-A2 METHOD OF FORMING A CROSSLINKED POLY(ARYLENE ETHER) FILM, AND FILM FORMED THEREBY SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-08-21 WO disclosed
CN-101111312-A Process for preparing aromatic carboxylic acids PROCESS DESIGN CT B V (NL) 2008-01-23 CN disclosed
US-6506740-B1 Compounds that can be substituted at the 7, 8, and/or 9 positions and methods for preparing the 4- dedimethylamino tetracycline compounds. Other tetracycline compounds are the 4-dedimethylaminotetracycline derivatives with an oxime GALDERMA LABORATORIES INC. 2003-01-14 US disclosed
CN-1359400-A Oil-free oxidatively curable polyester compositions EASTMAN CHEM CO (US) 2002-07-17 CN disclosed
EP-0704416-B1 Manufacture of high purity benzene and para-rich xylenes by combining aromatization and selective disproportionation of impure toluene CHEVRON CHEM CO (US) 2000-01-12 EP disclosed
US-5041227-A Continous recycling of extractant BEND RESEARCH, INC. 1991-08-20 US disclosed
US-4017547-A CATALYTIC, OXIDES OF TUNGSTEN, MOLYBDENUM, AND BISMUTH EASTMAN KODAK COMPANY (US) 1977-04-12 US disclosed