Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12308903 | 0.83 | — | — | |
| SCHEMBL12335220 | 0.82 | DGAT1 (0.30) | — | |
| SCHEMBL12335915 | 0.81 | HPGD (0.38) | — | |
| SCHEMBL12308392 | 0.77 | — | — | |
| SCHEMBL18016458 | 0.76 | LMNA (0.36) | — | |
| SCHEMBL12308900 | 0.75 | — | — | |
| SCHEMBL12335914 | 0.73 | HPGD (0.40) | — | |
| SCHEMBL4130706 | 0.71 | TSHR (0.38) | — | |
| SCHEMBL12308389 | 0.69 | GRM2 (0.33) | — | |
| SCHEMBL12308849 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2006286-A9 | ISOXAZOLE DERIVATIVE AND ISOTHIAZOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON 11 BETA -HYDROXYSTEROID DEHYDROGENASE TYPE I | Shionogi Co., Ltd. (JP) | 2009-07-22 | — | — | EP | disclosed |
| EP-2006286-A2 | ISOXAZOLE DERIVATIVE AND ISOTHIAZOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON 11 BETA -HYDROXYSTEROID DEHYDROGENASE TYPE I | Shionogi Co., Ltd. (JP) | 2008-12-24 | — | — | EP | disclosed |