Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | PTPRE | P23469 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5837033 | 0.86 | PTPRC (0.42) | HPGDALDH1A1L3MBTL1HTTPTPRC | |
| SCHEMBL13768422 | 0.77 | MAPT (0.46) | HPGDALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL22775116 | 0.74 | HPGD (0.56) | HPGDALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL1121822 | 0.74 | HPGD (0.60) | HPGDALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL29503118 | 0.73 | HPGD (0.63) | HPGDALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL3647943 | 0.71 | CFTR (0.40) | HPGDALDH1A1L3MBTL1HTTPTPRC | |
| SCHEMBL18723612 | 0.71 | WNT3A (0.32) | HPGDALDH1A1 | |
| SCHEMBL21962471 | 0.71 | WNT3A (0.31) | — | |
| SCHEMBL18723628 | 0.70 | HPGD (0.31) | HPGDSMN1; SMN2 | |
| SCHEMBL3715448 | 0.69 | PTPRC (0.42) | HPGDALDH1A1L3MBTL1HTTPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114222574-B | Inhibition of USP36 | 瓦洛健康股份有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-114222574-A | Inhibition of USP36 | 瓦洛健康股份有限公司 | 2022-03-22 | — | — | CN | disclosed |
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |