Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009963 | 0.89 | MAPT (0.46) | MAPTTDP1TP53L3MBTL1HPGD | |
| SCHEMBL5260554 | 0.80 | MAPT (0.62) | MAPTTDP1TP53L3MBTL1HPGD | |
| SCHEMBL1379362 | 0.80 | MAPT (0.65) | MAPTTDP1TP53L3MBTL1HPGD | |
| SCHEMBL1425934 | 0.79 | ADORA1 (0.50) | MAPTTDP1TP53L3MBTL1HPGD | |
| SCHEMBL23833453 | 0.78 | MAPT (0.66) | MAPTTDP1TP53L3MBTL1HPGD | |
| SCHEMBL13768804 | 0.77 | HPGD (0.39) | MAPTL3MBTL1HPGDALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL31699313 | 0.77 | ADORA1 (0.50) | MAPTTDP1TP53L3MBTL1HPGD | |
| SCHEMBL13768306 | 0.76 | L3MBTL1 (0.43) | MAPTTDP1TP53L3MBTL1HPGD | |
| SCHEMBL6318336 | 0.75 | ADORA1 (0.59) | MAPTTDP1TP53L3MBTL1HPGD | |
| SCHEMBL17321000 | 0.74 | L3MBTL1 (0.65) | MAPTTDP1TP53L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114222574-B | Inhibition of USP36 | 瓦洛健康股份有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-114222574-A | Inhibition of USP36 | 瓦洛健康股份有限公司 | 2022-03-22 | — | — | CN | disclosed |
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |