SCHEMBL137689

SCHEMBL137689

Cc1cc(=O)oc2cc(OS(=O)(=O)c3ccc([N+](=O)[O-])c4ccccc34)ccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPL P05186 6/20 0.67
ALPI P09923 5/20 0.67
KDM4E B2RXH2 8/20 0.55
ALDH1A1 P00352 7/20 0.55
GAA P10253 4/20 0.55
CA2 P00918 1/20 0.54
STS P08842 1/20 0.54
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
POLB P06746 2/20 0.53
MAPT P10636 3/20 0.53
LMNA P02545 2/20 0.53
GLA P06280 2/20 0.53
THRB P10828 1/20 0.53
HTT P42858 1/20 0.53
TDP1 Q9NUW8 3/20 0.49
BLM P54132 1/20 0.49
MAOB P27338 2/20 0.48
HPGD P15428 2/20 0.47
HSD17B10 Q99714 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31120327 0.84 ALPL (0.81) ALPLALPIKDM4EALDH1A1GAA
SCHEMBL17856881 0.81 ALPL (0.63) ALPLALPIKDM4EALDH1A1GAA
SCHEMBL17861141 0.81 ALPL (0.63) ALPLALPIKDM4EALDH1A1GAA
SCHEMBL137684 0.78 ALPL (0.78) ALPLALPIKDM4EALDH1A1GAA
SCHEMBL10850733 0.77 MAOB (0.70) ALPLALPIKDM4EALDH1A1GAA
SCHEMBL10850744 0.74 ALPL (0.84) ALPLALPISTSMAOBHPGD
SCHEMBL13930283 0.73 MAOB (0.71) ALPLALPIKDM4EALDH1A1GAA
SCHEMBL3761324 0.72 KDM4E (0.74) ALPLALPIKDM4EALDH1A1GAA
Potassium Ion SCHEMBL380405 0.72 KDM4E (0.74) ALPLALPIKDM4EALDH1A1GAA
SCHEMBL14129341 0.72 MAOB (0.66) KDM4EALDH1A1GAACA2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10889849-B2 Oxidized glutathione assay PROMEGA CORPORATION (US) 2021-01-12 US disclosed
US-20180030503-A1 OXIDIZED GLUTATHIONE ASSAY JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2018-02-01 US disclosed
US-20180030503-A1 OXIDIZED GLUTATHIONE ASSAY JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2018-02-01 US disclosed
US-9816127-B2 Oxidized glutathione assay PROMEGA CORPORATION (US) 2017-11-14 US disclosed
US-9816127-B2 Oxidized glutathione assay PROMEGA CORPORATION (US) 2017-11-14 US disclosed
EP-2611929-B1 OXIDIZED GLUTATHIONE ASSAY PROMEGA CORP (US) 2016-01-13 EP disclosed
US-20120058501-A1 OXIDIZED GLUTATHIONE ASSAY JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2012-03-08 US disclosed
US-20120058501-A1 OXIDIZED GLUTATHIONE ASSAY JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2012-03-08 US disclosed
WO-2012030960-A1 OXIDIZED GLUTATHIONE ASSAY PROMEGA CORPORATION (US) 2012-03-08 WO disclosed