Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.74 |
| ▸ | GAA | P10253 | 5/20 | 0.74 |
| ▸ | STS | P08842 | 2/20 | 0.72 |
| ▸ | CA2 | P00918 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | ALPL | P05186 | 3/20 | 0.62 |
| ▸ | ALPI | P09923 | 3/20 | 0.62 |
| ▸ | GLA | P06280 | 4/20 | 0.58 |
| ▸ | MAOA | P21397 | 4/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3761324 | 0.97 | KDM4E (0.74) | KDM4EALDH1A1GAASTSCA2 | |
| SCHEMBL10850187 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1GAASTSCA2 | |
| SCHEMBL38662608 | 0.84 | ALDH1A1 (0.76) | KDM4EALDH1A1GAASTSCA2 | |
| SCHEMBL25184 | 0.84 | ALDH1A1 (0.76) | KDM4EALDH1A1GAASTSCA2 | |
| SCHEMBL30139608 | 0.84 | ALDH1A1 (0.76) | KDM4EALDH1A1GAASTSCA2 | |
| SCHEMBL9451464 | 0.84 | STS (1.00) | KDM4EALDH1A1GAASTSCA2 | |
| SCHEMBL3761326 | 0.83 | ALDH1A1 (0.74) | KDM4EALDH1A1GAASTSCA2 | |
| SCHEMBL1358798 | 0.82 | KDM4E (0.72) | KDM4EALDH1A1GAASTSCA2 | |
| SCHEMBL13930283 | 0.81 | MAOB (0.71) | KDM4EALDH1A1GAASTSCA2 | |
| SCHEMBL31120406 | 0.81 | ALDH1A1 (0.71) | KDM4EALDH1A1GAASTSCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120028551-A | Construction method and application of diagnosis marker combination and ovarian endometriosis prediction model | 南京市妇幼保健院 | 2025-05-23 | — | — | CN | claimed |
| WO-2024177860-A1 | IN CHEMICO TEST FOR TOXICITY | LEBRUN LABS LLC (US) | 2024-08-29 | — | — | WO | claimed |
| CN-110632052-A | Fluorescence spectrum detection method for activity of soil arylsulfatase | 山西师范大学 | 2019-12-31 | — | — | CN | claimed |
| US-20190040446-A1 | METHOD FOR ASSAYING ARYLSULFATASE ACTIVITY | GODO SHUSEI CO., LTD. (JP) | 2019-02-07 | — | — | US | claimed |
| EP-2687598-B1 | METHOD FOR ASSAYING ARYLSULFATASE ACTIVITY | GODO SHUSEI KK (JP) | 2017-02-15 | — | — | EP | claimed |
| US-20170029865-A1 | METHOD FOR ASSAYING ARYLSULFATASE ACTIVITY | GODO SHUSEI CO., LTD. (JP) | 2017-02-02 | — | — | US | claimed |
| US-20140087404-A1 | METHOD FOR ASSAYING ARYLSULFATASE ACTIVITY | GODO SHUSEI CO., LTD. (JP) | 2014-03-27 | — | — | US | claimed |
| EP-2687598-A1 | METHOD FOR ASSAYING ARYLSULFATASE ACTIVITY | Godo Shusei Co., Ltd. (JP) | 2014-01-22 | — | — | EP | claimed |
| US-12559784-B2 | In chemico test for toxicity | LEBRUN LABS LLC (US) | 2026-02-24 | — | — | US | disclosed |
| US-20250369032-A1 | IN CHEMICO TEST FOR TOXICITY | LEBRUN LABS LLC (US) | 2025-12-04 | — | — | US | disclosed |
| CN-120028551-A | Construction method and application of diagnosis marker combination and ovarian endometriosis prediction model | 南京市妇幼保健院 | 2025-05-23 | — | — | CN | disclosed |
| US-20250101489-A1 | IN CHEMICO TEST FOR TOXICITY | LEBRUN LABS LLC | 2025-03-27 | — | — | US | disclosed |
| US-20250026846-A1 | Novel Anti-Human Transferrin Receptor Antibody Capable of Penetrating Blood-Brain Barrier | JCR PHARMACEUTICALS CO., LTD. (JP) | 2025-01-23 | — | — | US | disclosed |
| US-RE50240-E1 | Anti-human transferrin receptor antibody capable of penetrating blood-brain barrier | JCR PHARMACEUTICALS CO., LTD. (JP) | 2024-12-24 | — | — | US | disclosed |
| US-20060145091-A1 | Self indicating radiation alert dosimeter | JP LABORATORIES INC. | 2006-07-06 | — | — | US | disclosed |
| EP-1599744-A2 | SELF-INDICATING RADIATION ALERT DOSIMETER | JP LABORATORIES, INC. (US) | 2005-11-30 | — | — | EP | disclosed |
| US-20050233389-A1 | Methods and compositions for peptide and protein labeling | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-10-20 | — | — | US | disclosed |
| US-20040209317-A1 | Methods and compositions for peptide and protein labeling | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2004-10-21 | — | — | US | disclosed |
| WO-2004077097-A2 | SELF-INDICATING RADIATION ALERT DOSIMETER | JP LABORATORIES INC. (US) | 2004-09-10 | — | — | WO | disclosed |
| US-6472167-B1 | MEASURE VIABLE BACTERIA AS A FUNCTION OF THE ACTIVITIES OF BACTERIAL ENZYMES, PHOSPHATASES, GLUCOSIDASES, AND AMINOPEPTIDASES; PRESENCE DETECTED BY A FLUORESCENT SIGNAL | BIOCONTROL SYSTEMS, INC. | 2002-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050233389-A1 | Methods and compositions for peptide and protein labeling | HLCS, BTD, QPCTL | KDM4E 3349/4885ALDH1A1 4372/4885GAA 4031/4885 |
| US-12559784-B2 | In chemico test for toxicity | ALPP, ALPI, CUTA | KDM4E 2591/4885ALDH1A1 274/4885GAA 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.