Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.40 |
| ▸ | PGR | P06401 | 6/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10089113 | 0.76 | AR (0.48) | ARPGRNR3C2SERPINA6SLC22A1 | |
| SCHEMBL4213846 | 0.73 | AR (0.46) | ARPGRNR3C2LMNASERPINA6 | |
| SCHEMBL7703808 | 0.69 | SHBG (0.59) | ARPGRNR3C2MAPTLMNA | |
| SCHEMBL30140884 | 0.69 | SHBG (0.59) | ARPGRNR3C2MAPTLMNA | |
| SCHEMBL2832958 | 0.69 | SHBG (0.59) | ARPGRNR3C2MAPTLMNA | |
| SCHEMBL14200096 | 0.69 | CYP17A1 (0.54) | ARPGRNR3C2MAPTLMNA | |
| SCHEMBL8843324 | 0.69 | CYP17A1 (0.54) | ARPGRNR3C2MAPTLMNA | |
| SCHEMBL12101456 | 0.69 | CYP17A1 (0.54) | ARPGRNR3C2MAPTLMNA | |
| SCHEMBL4261966 | 0.69 | AR (0.50) | ARPGRNR3C2MAPTLMNA | |
| SCHEMBL13397495 | 0.69 | CYP17A1 (0.54) | ARPGRNR3C2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083272-A2 | 19-NOR-STEROID DERIVATIVES WITH A 15α,16α-METHYLENE GROUP AND A SATURATED 17,17-SPIROLACTONE RING, USE THEREOF, AND MEDICAMENTS CONTAINING SAID DERIVATIVES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |