Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.50 |
| ▸ | PGR | P06401 | 6/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.50 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953448 | 0.86 | AR (0.46) | ARPGRNR3C2SERPINA6ALDH1A1 | |
| SCHEMBL29335494 | 0.86 | AR (0.51) | ARPGRNR3C2SERPINA6ALDH1A1 | |
| SCHEMBL2833823 | 0.86 | AR (0.51) | ARPGRNR3C2SERPINA6ALDH1A1 | |
| SCHEMBL29335775 | 0.86 | AR (0.51) | ARPGRNR3C2SERPINA6ALDH1A1 | |
| SCHEMBL13216960 | 0.83 | AR (0.48) | ARPGRNR3C2SERPINA6ALDH1A1 | |
| SCHEMBL29335510 | 0.82 | AR (0.49) | ARPGRNR3C2SERPINA6ALDH1A1 | |
| SCHEMBL13474752 | 0.82 | AR (0.49) | ARPGRNR3C2SERPINA6ALDH1A1 | |
| SCHEMBL7703808 | 0.82 | SHBG (0.59) | ARPGRNR3C2SERPINA6ALDH1A1 | |
| SCHEMBL2832958 | 0.82 | SHBG (0.59) | ARPGRNR3C2SERPINA6ALDH1A1 | |
| SCHEMBL30140884 | 0.82 | SHBG (0.59) | ARPGRNR3C2SERPINA6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090062236-A1 | Programmable genotoxic agents and uses therefor | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-03-05 | — | — | US | disclosed |
| US-7169611-B2 | Programmable genotoxic agents and uses therefor | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-01-30 | — | — | US | disclosed |
| US-20030220311-A1 | Programmable genotoxic agents and uses therefor | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2003-11-27 | — | — | US | disclosed |
| US-6500669-B1 | FOR SELECTIVELY KILLING A SUBPOPULATION OF CELLS IN A HETEROGENOUS CELL POPULATION; ALKYLATING AGENTS OR HEAVY METAL COORDINATION COMPOUNDS LINKED TO A COMPOUND THAT BINDS TO STEROID RECEPTOR | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2002-12-31 | — | — | US | disclosed |