Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.43 |
| ▸ | PGR | P06401 | 5/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3766911 | 0.74 | AR (0.51) | ARPGRNR3C2LMNAESR1 | |
| SCHEMBL13769268 | 0.73 | AR (0.38) | ARPGRNR3C2 | |
| SCHEMBL13769267 | 0.73 | AR (0.38) | ARPGRNR3C2 | |
| SCHEMBL13473575 | 0.72 | AR (0.46) | ARPGRNR3C2LMNAESR1 | |
| SCHEMBL4106357 | 0.72 | AR (0.46) | ARPGRNR3C2LMNAESR1 | |
| SCHEMBL6841944 | 0.72 | AR (0.55) | ARPGRNR3C2LMNAESR1 | |
| SCHEMBL6841943 | 0.72 | AR (0.55) | ARPGRNR3C2LMNAESR1 | |
| SCHEMBL13769017 | 0.72 | AR (0.44) | ARPGRNR3C2LMNAESR1 | |
| SCHEMBL3773112 | 0.72 | AR (0.48) | ARPGRNR3C2LMNA | |
| SCHEMBL13797697 | 0.70 | AR (0.44) | ARPGRNR3C2LMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083272-A2 | 19-NOR-STEROID DERIVATIVES WITH A 15α,16α-METHYLENE GROUP AND A SATURATED 17,17-SPIROLACTONE RING, USE THEREOF, AND MEDICAMENTS CONTAINING SAID DERIVATIVES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |