Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.38 |
| ▸ | PGR | P06401 | 3/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13769268 | 1.00 | AR (0.38) | ARPGRNR3C2PDK1PDK2 | |
| SCHEMBL13768996 | 0.73 | AR (0.43) | ARPGRNR3C2 | |
| SCHEMBL6841944 | 0.70 | AR (0.55) | ARPGRNR3C2 | |
| SCHEMBL6841943 | 0.70 | AR (0.55) | ARPGRNR3C2 | |
| SCHEMBL11862137 | 0.68 | AR (0.52) | ARPGRNR3C2 | |
| SCHEMBL6692321 | 0.68 | AR (0.52) | ARPGRNR3C2 | |
| SCHEMBL13769016 | 0.67 | AR (0.50) | ARPGRNR3C2 | |
| SCHEMBL4108635 | 0.66 | AR (0.55) | ARPGRNR3C2 | |
| SCHEMBL4261966 | 0.66 | AR (0.50) | ARPGRNR3C2PDK1PDK2 | |
| SCHEMBL13769021 | 0.66 | PGR (0.52) | ARPGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083266-A1 | 17-HYDROXY-19-NOR-21-CARBOXYLIC ACID-STEROID γ-LACTONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING THE DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |