Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31558612 | 0.84 | MAOB (0.64) | MAOBADORA3HSD17B3MAOACA12 | |
| SCHEMBL8344553 | 0.84 | MAOB (0.64) | MAOBADORA3HSD17B3MAOACA12 | |
| SCHEMBL10791744 | 0.81 | HSD17B3 (0.74) | MAOBHSD17B3DYRK1AMAOACA12 | |
| SCHEMBL28994275 | 0.81 | CA12 (0.57) | MAOBADORA3HSD17B3SLC6A2SLC6A4 | |
| SCHEMBL266449 | 0.81 | MAOA (0.61) | MAOBHSD17B3MAOACA12CA1 | |
| SCHEMBL16284310 | 0.81 | NPC1 (0.57) | MAOBADORA3HSD17B3MAOASLC6A2 | |
| SCHEMBL15842923 | 0.79 | HSD17B3 (0.60) | MAOBADORA3HSD17B3SLC6A2SLC6A4 | |
| SCHEMBL16284307 | 0.78 | SLC16A3 (0.48) | MAOBADORA3HSD17B3SLC6A2SLC6A4 | |
| SCHEMBL10263015 | 0.78 | HSD17B3 (0.47) | MAOBADORA3HSD17B3MAOASLC6A2 | |
| SCHEMBL31202673 | 0.78 | ADAM17 (0.52) | MAOBADORA3HSD17B3MAOASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709699-B1 | CONJUGATED POLYMERS, REPRESENTATION THEREOF, AND USE OF THE SAME | MERCK PATENT GMBH (DE) | 2009-07-01 | — | — | EP | disclosed |
| US-20070123690-A1 | Conjugated polymers, representation thereof, and use of the same | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
| US-20070123690-A1 | Conjugated polymers, representation thereof, and use of the same | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |