Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.63 |
| ▸ | PGR | P06401 | 7/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.53 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.53 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.53 |
| ▸ | AR | P10275 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12949523 | 0.87 | PGR (0.66) | PGRSLC6A4NR3C1ARLMNA | |
| SCHEMBL16404180 | 0.81 | PGR (0.78) | NR1I2PGRSLC6A4NR3C1ADORA3 | |
| SCHEMBL22382702 | 0.81 | NR1I2 (0.74) | NR1I2PGRSLC6A4NR3C1ADORA3 | |
| SCHEMBL12942957 | 0.80 | PGR (0.57) | NR1I2PGRSLC6A4NR3C1ADORA3 | |
| Norelgestromin SCHEMBL4814600 | 0.77 | NR1I2 (1.00) | NR1I2PGRSLC6A4NR3C1ADORA3 | |
| SCHEMBL13306245 | 0.77 | NR1I2 (0.78) | NR1I2PGRSLC6A4NR3C1ADORA3 | |
| Norelgestromin SCHEMBL4814611 | 0.77 | NR1I2 (1.00) | NR1I2PGRSLC6A4NR3C1ADORA3 | |
| Norelgestromin SCHEMBL3267125 | 0.77 | NR1I2 (1.00) | NR1I2PGRSLC6A4NR3C1ADORA3 | |
| Norelgestromin SCHEMBL118611 | 0.77 | NR1I2 (1.00) | NR1I2PGRSLC6A4NR3C1ADORA3 | |
| Norelgestromin SCHEMBL3163347 | 0.77 | NR1I2 (1.00) | NR1I2PGRSLC6A4NR3C1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083266-A1 | 17-HYDROXY-19-NOR-21-CARBOXYLIC ACID-STEROID γ-LACTONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING THE DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |