Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.50 |
| ▸ | MTOR | P42345 | 4/20 | 0.50 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20740433 | 0.94 | L3MBTL3 (0.46) | PIK3CAMTORL3MBTL3L3MBTL1CHRNB2 | |
| SCHEMBL20740477 | 0.94 | HRH3 (0.48) | PIK3CAMTORL3MBTL3L3MBTL1DRD2 | |
| SCHEMBL20740505 | 0.92 | L3MBTL3 (0.45) | PIK3CAMTORL3MBTL3L3MBTL1HSD11B1 | |
| SCHEMBL20740625 | 0.92 | L3MBTL3 (0.45) | PIK3CAMTORL3MBTL3L3MBTL1HSD11B1 | |
| SCHEMBL13769029 | 0.87 | L3MBTL3 (0.64) | L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL10126764 | 0.86 | ACVR1 (0.53) | PIK3CAMTORL3MBTL3L3MBTL1 | |
| SCHEMBL2724459 | 0.86 | L3MBTL3 (0.62) | L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL14916901 | 0.86 | PIK3CA (0.50) | PIK3CAMTORCHRNB2CHRNA4HSD11B1 | |
| SCHEMBL2300495 | 0.84 | MAP4K4 (0.49) | PIK3CAMTORL3MBTL3L3MBTL1CHRNB2 | |
| SCHEMBL2724584 | 0.83 | L3MBTL1 (0.46) | PIK3CAMTORL3MBTL3L3MBTL1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116924976-A | Diaryl heterocyclic amine compound, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2023-10-24 | — | — | CN | disclosed |
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |
| WO-2009085185-A1 | FUSED PYRIDINE, PYRIMIDINE AND TRIAZINE COMPOUNDS AS CELL CYCLE INHIBITORS | AMGEN INC. (US) | 2009-07-09 | — | — | WO | disclosed |