Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL19410620 | 1.00 | TSHR (0.50) | TSHRGAAALDH1A1L3MBTL1NLRP3 | |
| Phenol SCHEMBL19411862 | 0.88 | ESR2 (0.46) | TSHRGAAALDH1A1L3MBTL1NLRP3 | |
| Resorcinol SCHEMBL19410619 | 0.85 | ALDH1A1 (0.41) | TSHRGAAALDH1A1L3MBTL1NLRP3 | |
| Ether SCHEMBL3178710 | 0.82 | ESR2 (0.53) | TSHRGAAALDH1A1L3MBTL1MAOB | |
| Alcohol SCHEMBL7573294 | 0.80 | TSHR (0.54) | TSHRGAAALDH1A1L3MBTL1NLRP3 | |
| Benzonitrile SCHEMBL2493083 | 0.79 | TSHR (0.64) | TSHRGAAALDH1A1L3MBTL1MAOB | |
| SCHEMBL2818597 | 0.79 | TSHR (0.63) | TSHRGAAALDH1A1POLBIMPDH2 | |
| SCHEMBL57480 | 0.79 | TSHR (0.63) | TSHRGAAALDH1A1POLBIMPDH2 | |
| Water SCHEMBL19410621 | 0.79 | TSHR (0.63) | TSHRGAAALDH1A1POLBIMPDH2 | |
| SCHEMBL29352197 | 0.79 | TSHR (0.63) | TSHRGAAALDH1A1POLBIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2100926-B1 | Nanosized particles of phthalocyanine pigments | XEROX CORP (US) | 2017-04-12 | — | — | EP | disclosed |
| US-8530607-B2 | Aromatic ether and alkynyl containing phthalonitriles | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2013-09-10 | — | — | US | disclosed |
| US-8168359-B2 | Nanosized particles of phthalocyanine pigments | XEROX CORPORATION (US) | 2012-05-01 | — | — | US | disclosed |
| US-20110288254-A1 | AROMATIC ETHER AND ALKYNYL CONTAINING PHTHALONITRILES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2011-11-24 | — | — | US | disclosed |
| US-8039576-B2 | Aromatic ether and alkynyl containing phthalonitriles | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2011-10-18 | — | — | US | disclosed |
| EP-2100926-A2 | Nanosized particles of phthalocyanine pigments | Xerox Corporation (US) | 2009-09-16 | — | — | EP | disclosed |
| US-20090226835-A1 | NANOSIZED PARTICLES OF PHTHALOCYANINE PIGMENTS | XEROX CORPORATION (US) | 2009-09-10 | — | — | US | disclosed |
| US-20090069484-A1 | AROMATIC ETHER AND ALKYNYL CONTAINING PHTHALONITRILES | THE GOVERNMENT OF THE US, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288254-A1 | AROMATIC ETHER AND ALKYNYL CONTAINING PHTHALONITRILES | PNN, BECN1, ACIN1 | TSHR 4875/4885GAA 3875/4885ALDH1A1 1956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.