Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.45 |
| ▸ | PDE4A | P27815 | 3/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10087254 | 0.85 | KDM4E (0.41) | HSD17B10MEN1KMT2APKMALDH1A1 | |
| SCHEMBL1610317 | 0.73 | SMN1; SMN2 (0.42) | HSD17B10MEN1KMT2APKMPDE10A | |
| SCHEMBL1608908 | 0.73 | ALDH1A1 (0.43) | HSD17B10MEN1KMT2APKMPDE10A | |
| SCHEMBL1610198 | 0.73 | ALDH1A1 (0.48) | HSD17B10MEN1KMT2APKMPDE10A | |
| SCHEMBL1609730 | 0.73 | ALDH1A1 (0.41) | HSD17B10MEN1KMT2APKMALDH1A1 | |
| SCHEMBL20119601 | 0.72 | SMN1; SMN2 (0.48) | HSD17B10MEN1KMT2APKMALDH1A1 | |
| SCHEMBL1610521 | 0.72 | AURKA (0.43) | HSD17B10MEN1KMT2APKMPDE10A | |
| SCHEMBL2894152 | 0.71 | KDM4E (0.50) | HSD17B10MEN1KMT2AKDM4ELMNA | |
| SCHEMBL1610417 | 0.71 | SMN1; SMN2 (0.48) | MEN1KMT2AALDH1A1POLBHSP90AA1 | |
| SCHEMBL23498533 | 0.71 | ALDH1A1 (0.41) | HSD17B10MEN1KMT2APKMPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081112-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |