Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610147 | 0.85 | ALDH1A1 (0.36) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL1608908 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL10087254 | 0.81 | KDM4E (0.41) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL1611172 | 0.80 | RAB9A (0.51) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL1610198 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL1612383 | 0.77 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL2136872 | 0.77 | APP (0.50) | ALDH1A1KDM4EMAPTKMT2ATSHR | |
| SCHEMBL1610141 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL1610317 | 0.75 | SMN1; SMN2 (0.42) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL1610521 | 0.74 | AURKA (0.43) | ALDH1A1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115724-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120115724-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| CN-101938905-A | Chemical compounds | SYNGENTA LTD | 2011-01-05 | — | — | CN | disclosed |
| WO-2010125332-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | SYNGENTA LIMITED (GB) | 2010-11-04 | — | — | WO | disclosed |
| EP-2237669-A2 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009081112-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009081112-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | ALDH1A1 1562/4885KDM4E 2613/4885MAPT 2800/4885 |
| US-20120115724-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | TYMS, DHFR, UNG | ALDH1A1 3537/4885KDM4E 2202/4885MAPT 1617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.