Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13769256 | 0.89 | MAPK1 (0.42) | SYKTLR7DHFRVDRPPARD | |
| SCHEMBL13769817 | 0.88 | DGAT1 (0.52) | TLR7ALDH1A1GAAGFERDGAT1 | |
| SCHEMBL5533628 | 0.83 | SYK (0.42) | SYKTLR7SLC7A5CYP11B1CYP11B2 | |
| SCHEMBL13769816 | 0.80 | CA12 (0.54) | DHFR | |
| SCHEMBL1929079 | 0.77 | SLC7A5 (0.57) | SYKSLC7A5NPC1PKMHPGD | |
| SCHEMBL14759025 | 0.76 | CYP11B1 (0.54) | SYKSLC7A5CYP11B1CYP11B2NPC1 | |
| SCHEMBL13433607 | 0.76 | HSP90AB1 (0.53) | SYKSLC7A5CYP11B1CYP11B2NPC1 | |
| SCHEMBL3357160 | 0.75 | SLC7A5 (0.56) | SYKSLC7A5NPC1PKMHPGD | |
| SCHEMBL13460869 | 0.74 | SLC7A5 (0.49) | SYKSLC7A5CYP11B1CYP11B2NPC1 | |
| SCHEMBL3930520 | 0.74 | PRKCI (0.57) | SYKSLC7A5CYP11B1CYP11B2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081195-A1 | CARBAMOYL COMPOUNDS AS DGAT1 INHIBITORS 190 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |