Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 4/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13769253 | 0.89 | SYK (0.44) | VDRPPARDSYKDHFRTLR7 | |
| SCHEMBL5533583 | 0.84 | CNR2 (0.40) | CNR2HDAC1AKT1AKT2SIRT2 | |
| SCHEMBL5033493 | 0.79 | PTPN1 (0.54) | SIRT2FFAR1PTPN1 | |
| SCHEMBL13769817 | 0.78 | DGAT1 (0.52) | TLR7 | |
| SCHEMBL13769816 | 0.78 | CA12 (0.54) | DHFRCDK8 | |
| SCHEMBL9456168 | 0.78 | PTPN1 (0.55) | CNR2SIRT2FFAR1PTPN1 | |
| SCHEMBL5039697 | 0.76 | PTPN1 (0.54) | CNR2SIRT2FFAR1PTPN1 | |
| SCHEMBL31103174 | 0.76 | CNR2 (0.57) | CNR2SIRT2FFAR1PTPN1 | |
| SCHEMBL5538522 | 0.74 | DGAT1 (0.63) | FFAR1 | |
| SCHEMBL21476702 | 0.74 | FFAR1 (0.66) | SIRT2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081195-A1 | CARBAMOYL COMPOUNDS AS DGAT1 INHIBITORS 190 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |