Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13134453 | 0.93 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL13134452 | 0.85 | MMP8 (0.38) | ALDH1A1MEN1KMT2AMMP8PKM | |
| SCHEMBL13173276 | 0.84 | MEN1 (0.32) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL13134458 | 0.82 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL13134451 | 0.82 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL13134457 | 0.81 | MMP8 (0.36) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL13064101 | 0.81 | MMP8 (0.47) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL13173226 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL13063942 | 0.80 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL383194 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086192-A1 | BIODEGRADABLE PHOSPHATE PROTECTED NUCLEOTIDE DERIVATIVES AND THEIR USE AS CANCER, ANTI VIRAL AND ANTI PARASITIC AGENTS | ALIOS BIOPHARMA, INC. (US) | 2009-07-09 | — | — | WO | disclosed |