Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13736530 | 0.90 | SCN9A (0.36) | BRD4SCN9AALDH1A1NPSR1HPGD | |
| SCHEMBL13736143 | 0.88 | SCN9A (0.33) | BRD4SCN9AALDH1A1NPSR1ATM | |
| SCHEMBL3724713 | 0.82 | PKM (0.37) | BRD4SCN9AALDH1A1NPSR1ATM | |
| SCHEMBL769188 | 0.77 | ALDH1A1 (0.40) | SCN9AALDH1A1NPSR1ATMSMN1; SMN2 | |
| SCHEMBL773870 | 0.76 | SCN9A (0.39) | SCN9AALDH1A1NPSR1ATMSMN1; SMN2 | |
| SCHEMBL3721352 | 0.75 | PDE4D (0.35) | BRD4SCN9AALDH1A1NPSR1ATM | |
| SCHEMBL13734752 | 0.75 | HDAC1 (0.36) | SCN9AALDH1A1NPSR1SMN1; SMN2HPGD | |
| SCHEMBL3726576 | 0.75 | SCN9A (0.37) | BRD4SCN9AALDH1A1NPSR1HPGD | |
| SCHEMBL771574 | 0.73 | SCN9A (0.37) | BRD4SCN9AALDH1A1NPSR1ATM | |
| SCHEMBL4826344 | 0.72 | SCN9A (0.41) | SCN9AALDH1A1NPSR1ATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086139-A1 | CONDENSED PENTACYCLIC DERIVATIVES FOR USE IN THE TREATMENT OF FLAVIVIRIDAE INFECTIONS | GENELABS TECHNOLOGIES, INC. (US) | 2009-07-09 | — | — | WO | disclosed |