SCHEMBL1377014

SCHEMBL1377014

Cc1ccc(N(C)S(=O)(=O)c2ccc(N3CCNCC3)c3ccccc23)cc1Cl

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 17/20 0.51
ADRB1 P08588 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1383346 0.87 HTR6 (0.55) HTR6ADRB1
SCHEMBL1378745 0.86 HTR6 (0.56) HTR6ADRB1
SCHEMBL3655977 0.85 HTR6 (0.53) HTR6
SCHEMBL1378251 0.82 HTR6 (0.52) HTR6ADRB1
SCHEMBL1380282 0.81 HTR6 (0.56) HTR6ADRB1
SCHEMBL1379064 0.81 HTR6 (0.53) HTR6ADRB1
SCHEMBL1377314 0.80 HTR6 (0.50) HTR6ADRB1
SCHEMBL1381952 0.80 HTR6 (0.49) HTR6
SCHEMBL1376935 0.80 HTR6 (0.49) HTR6
SCHEMBL1374538 0.78 HTR6 (0.50) HTR6ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4731114-B2 2011-07-20 JP claimed