Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | NCF1 | P14598 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MYLK | Q15746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383346 | 0.85 | HTR6 (0.55) | HTR6HTR2ANCF1CYP1A2CYP2D6 | |
| SCHEMBL1378745 | 0.84 | HTR6 (0.56) | HTR6HTR2ANCF1CYP1A2CYP2D6 | |
| SCHEMBL1379064 | 0.81 | HTR6 (0.53) | HTR6NCF1KMT2AHTR3EHTR3B | |
| SCHEMBL3655977 | 0.81 | HTR6 (0.53) | HTR6HTR2ANCF1CYP1A2CYP2D6 | |
| SCHEMBL1378319 | 0.81 | HTR6 (0.50) | HTR6HTR2AMAPTHTR1AHTR1D | |
| SCHEMBL1377014 | 0.80 | HTR6 (0.51) | HTR6 | |
| SCHEMBL1377836 | 0.79 | HTR6 (0.50) | HTR6HTR2ANCF1CYP1A2CYP2D6 | |
| SCHEMBL1380036 | 0.76 | HTR6 (0.56) | HTR6HTR2ANCF1CYP1A2CYP2D6 | |
| SCHEMBL1380282 | 0.76 | HTR6 (0.56) | HTR6HTR2ANCF1CYP1A2CYP2D6 | |
| SCHEMBL3621063 | 0.74 | HTR6 (0.64) | HTR6HTR2ANCF1MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4731114-B2 | — | — | 2011-07-20 | — | — | JP | claimed |