Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.59 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.59 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.59 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RNASEL | Q05823 | 3/20 | 0.49 |
| ▸ | HINT1 | P49773 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.49 |
| ▸ | GAPDH | P04406 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19158331 | 1.00 | P2RX3 (0.59) | P2RX3P2RX4P2RX2P2RY11MEN1 | |
| SCHEMBL18516358 | 0.93 | P2RY11 (0.58) | P2RX3P2RX4P2RX2P2RY11RNASEL | |
| SCHEMBL18516359 | 0.92 | P2RY11 (0.52) | P2RX3P2RX4P2RX2P2RY11RNASEL | |
| SCHEMBL6758742 | 0.92 | P2RX3 (0.59) | P2RX3P2RX4P2RX2P2RY11MEN1 | |
| SCHEMBL13224528 | 0.91 | P2RX3 (0.56) | P2RX3P2RX4P2RX2P2RY11MEN1 | |
| SCHEMBL13224543 | 0.91 | P2RX3 (0.56) | P2RX3P2RX4P2RX2P2RY11MEN1 | |
| SCHEMBL3448447 | 0.91 | P2RX3 (0.56) | P2RX3P2RX4P2RX2P2RY11MEN1 | |
| SCHEMBL10060178 | 0.90 | P2RX3 (0.58) | P2RX3P2RX4P2RX2P2RY11ALDH1A1 | |
| SCHEMBL10060175 | 0.90 | P2RX3 (0.58) | P2RX3P2RX4P2RX2P2RY11ALDH1A1 | |
| SCHEMBL1389470 | 0.90 | P2RX3 (0.58) | P2RX3P2RX4P2RX2P2RY11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009087066-A2 | METHOD FOR PREPARING A MARKED PURINE DERIVATIVE, SAID DERIVATIVE AND USES THEREOF | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2009-07-16 | — | — | WO | disclosed |