Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 16/20 | 0.78 |
| ▸ | SLC6A2 | P23975 | 16/20 | 0.78 |
| ▸ | SLC6A4 | P31645 | 16/20 | 0.78 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.78 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4009081 | 0.89 | HTR1A (0.65) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL4013368 | 0.87 | SLC6A2 (1.00) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL31060552 | 0.87 | SLC6A2 (1.00) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A | |
| Hydrochloric Acid SCHEMBL4007236 | 0.86 | SLC6A2 (0.97) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL7904960 | 0.84 | HTR1A (0.60) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL4005980 | 0.82 | HTR1A (0.70) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL14878659 | 0.81 | HTR1A (0.62) | HTR1ASLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL4157091 | 0.81 | SLC6A2 (0.80) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL4005157 | 0.80 | SLC6A2 (0.98) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7495157 | 0.80 | HTR1A (0.74) | HTR1ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |