Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 19/20 | 0.80 |
| ▸ | SLC6A4 | P31645 | 19/20 | 0.80 |
| ▸ | HTR1A | P08908 | 17/20 | 0.80 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.74 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13770272 | 0.89 | SLC6A4 (1.00) | SLC6A2SLC6A4HTR1ASLC6A3HTR6 | |
| Hydrochloric Acid SCHEMBL4009907 | 0.88 | SLC6A4 (0.98) | SLC6A2SLC6A4HTR1ASLC6A3HTR6 | |
| SCHEMBL13769617 | 0.85 | HTR1A (1.00) | SLC6A2SLC6A4HTR1ASLC6A3 | |
| Hydrochloric Acid SCHEMBL4005157 | 0.85 | SLC6A2 (0.98) | SLC6A2SLC6A4HTR1ASLC6A3 | |
| Hydrochloric Acid SCHEMBL4013707 | 0.84 | HTR1A (0.97) | SLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL4704178 | 0.83 | SLC6A2 (0.73) | SLC6A2SLC6A4HTR1ASLC6A3HTR6 | |
| SCHEMBL13770271 | 0.81 | HTR1A (0.78) | SLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL13769471 | 0.81 | SLC6A4 (1.00) | SLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL4010653 | 0.80 | HTR1A (0.53) | SLC6A2SLC6A4HTR1ASLC6A3 | |
| Hydrochloric Acid SCHEMBL4014487 | 0.80 | SLC6A4 (0.98) | SLC6A2SLC6A4HTR1ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |