Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13013650 | 0.76 | AR (0.55) | NR1I2SLC6A4NR3C1PGRADORA3 | |
| SCHEMBL16404187 | 0.75 | PGR (0.57) | NR1I2SLC6A4NR3C1PGRADORA3 | |
| SCHEMBL13769020 | 0.74 | PGR (0.41) | SLC6A4NR3C1PGRPDE4DMEN1 | |
| SCHEMBL13770457 | 0.71 | PDK1 (0.60) | NR1I2SLC6A4NR3C1PGRADORA3 | |
| SCHEMBL13770151 | 0.71 | PGR (0.59) | SLC6A4NR3C1PGRMEN1CYP3A4 | |
| SCHEMBL13770458 | 0.70 | PGR (0.45) | NR1I2SLC6A4NR3C1PGRADORA3 | |
| SCHEMBL13770153 | 0.69 | AR (0.59) | SLC6A4NR3C1PGRMEN1CYP3A4 | |
| SCHEMBL12904848 | 0.69 | NR1I2 (0.39) | NR1I2SLC6A4NR3C1PGRADORA3 | |
| SCHEMBL12942943 | 0.69 | PGR (0.42) | NR1I2SLC6A4NR3C1PGRADORA3 | |
| SCHEMBL22382735 | 0.69 | NR1I2 (0.64) | NR1I2SLC6A4NR3C1PGRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083268-A2 | 17-(1'-PROPENYL)-17-3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |