Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1379962 | 0.91 | PGR (0.37) | PGRCYP2C19 | |
| SCHEMBL1376889 | 0.86 | PGR (0.48) | PGRCYP2C19CYP2C9CYP2D6KCNH2 | |
| SCHEMBL1376545 | 0.86 | PGR (0.48) | PGRCYP2C19CYP2C9CYP2D6KCNH2 | |
| SCHEMBL1377127 | 0.86 | PGR (0.45) | PGRCYP2C19CYP2C9CYP2D6KCNH2 | |
| SCHEMBL1377211 | 0.84 | PGR (0.46) | PGRCYP2C19CYP2C9CYP2D6KCNH2 | |
| SCHEMBL1379593 | 0.83 | PGR (0.46) | PGRCYP2C19CYP2C9CYP2D6KCNH2 | |
| SCHEMBL1380583 | 0.83 | PGR (0.48) | PGRCYP2C19CYP2C9CYP2D6 | |
| SCHEMBL1377099 | 0.81 | PGR (0.42) | PGRCYP2C19CYP2C9CYP2D6KCNH2 | |
| SCHEMBL1377609 | 0.80 | PGR (0.52) | PGRCYP2C19CYP2C9CYP2D6KCNH2 | |
| SCHEMBL1377611 | 0.80 | PGR (0.52) | PGRCYP2C19CYP2C9CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4805909-B2 | — | — | 2011-11-02 | — | — | JP | claimed |
| EP-1725522-A1 | ANILINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-11-29 | — | — | EP | claimed |
| WO-2005085185-A1 | ANILINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-09-15 | — | — | WO | claimed |
| EP-1725522-A1 | ANILINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005085185-A1 | ANILINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-09-15 | — | — | WO | disclosed |