Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 19/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1380657 | 0.91 | AR (0.50) | PGRAR | |
| SCHEMBL1376534 | 0.88 | AR (0.63) | PGRAR | |
| SCHEMBL1380580 | 0.87 | PGR (0.46) | PGRARCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL1380589 | 0.86 | PGR (0.49) | PGRARCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL3289101 | 0.86 | PGR (0.49) | PGRARCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL1379860 | 0.83 | PGR (0.47) | PGRARCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL1377129 | 0.83 | PGR (0.47) | PGRCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL1378130 | 0.82 | PGR (0.46) | PGRARCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL1378604 | 0.81 | PGR (0.43) | PGRARCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL1377453 | 0.79 | PGR (0.59) | PGRARCYP2C19CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4805909-B2 | — | — | 2011-11-02 | — | — | JP | claimed |
| EP-1725522-A1 | ANILINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-11-29 | — | — | EP | claimed |
| WO-2005085185-A1 | ANILINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-09-15 | — | — | WO | claimed |
| EP-1725522-A1 | ANILINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005085185-A1 | ANILINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-09-15 | — | — | WO | disclosed |