Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 14/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1391849 | 0.87 | IDH2 (0.48) | IDH2SLC2A1APPLMNAMAPT | |
| SCHEMBL1392072 | 0.82 | IDH2 (0.62) | IDH2SLC2A1APPLMNAMAPT | |
| SCHEMBL10244885 | 0.81 | IDH2 (0.46) | IDH2SLC2A1LMNAMAPTMAPK1 | |
| SCHEMBL10244123 | 0.76 | APP (0.67) | IDH2SLC2A1APPLMNAMAPT | |
| SCHEMBL10245089 | 0.76 | APP (0.67) | IDH2SLC2A1APPLMNAMAPT | |
| SCHEMBL10244162 | 0.75 | APP (0.62) | IDH2SLC2A1APPLMNAMAPT | |
| SCHEMBL10245074 | 0.73 | KCNH3 (0.67) | IDH2SLC2A1APPLMNAMAPT | |
| SCHEMBL13771742 | 0.72 | IDH2 (0.71) | IDH2SLC2A1APPLMNAMAPT | |
| SCHEMBL1390920 | 0.72 | APP (0.61) | IDH2SLC2A1APPLMNAMAPT | |
| SCHEMBL1391225 | 0.72 | LMNA (0.57) | IDH2SLC2A1APPLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009091388-A2 | TRIAZINES AND RELATED COMPOUNDS HAVING ANTIVIRAL ACTIVITY, COMPOSITIONS AND METHODS THEREOF | PROGENICS PHARMACEUTICALS, INC. (US) | 2009-07-23 | — | — | WO | disclosed |