Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.73 |
| ▸ | TSHR | P16473 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063013 | 0.88 | TDP1 (0.85) | TDP1TSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL11170707 | 0.88 | ALDH1A1 (0.64) | TDP1TSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL30416074 | 0.88 | TDP1 (0.85) | TDP1TSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL12083356 | 0.85 | TDP1 (1.00) | TDP1TSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL9765812 | 0.85 | TDP1 (0.92) | TDP1TSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL27279033 | 0.85 | TDP1 (0.67) | TDP1TSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL15402 | 0.83 | TDP1 (0.76) | TDP1TSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL6063097 | 0.83 | TDP1 (0.76) | TDP1TSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL15397549 | 0.83 | TDP1 (0.89) | TDP1TSHRLMNAALDH1A1L3MBTL1 | |
| Ethylene Glycol SCHEMBL432445 | 0.83 | TDP1 (0.76) | TDP1TSHRLMNAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2075011-A2 | Prodrugs Containing Bio-Cleavable Linkers | Piramal Life Sciences Limited (IN) | 2009-07-01 | — | — | EP | disclosed |