Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.76 |
| ▸ | TSHR | P16473 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063013 | 0.94 | TDP1 (0.85) | TDP1TSHRNPC1RAB9ALMNA | |
| SCHEMBL30416074 | 0.94 | TDP1 (0.85) | TDP1TSHRNPC1RAB9ALMNA | |
| SCHEMBL29392370 | 0.92 | TDP1 (0.76) | TDP1TSHRNPC1RAB9ALMNA | |
| SCHEMBL15402 | 0.92 | TDP1 (0.76) | TDP1TSHRNPC1RAB9ALMNA | |
| SCHEMBL11308627 | 0.90 | TDP1 (0.67) | TDP1TSHRNPC1RAB9ALMNA | |
| SCHEMBL12083353 | 0.89 | TDP1 (0.83) | TDP1TSHRNPC1RAB9ALMNA | |
| Ethylene SCHEMBL290827 | 0.89 | TDP1 (0.71) | TDP1TSHRNPC1RAB9ALMNA | |
| SCHEMBL29637124 | 0.89 | TDP1 (0.83) | TDP1TSHRNPC1RAB9ALMNA | |
| SCHEMBL6061655 | 0.89 | TDP1 (0.76) | TDP1TSHRNPC1RAB9ALMNA | |
| SCHEMBL6062602 | 0.89 | TDP1 (0.76) | TDP1TSHRNPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2921162-B1 | OIL-IN-WATER EMULSION COMPOSITION | KAO CORP (JP) | 2017-08-02 | — | — | EP | claimed |
| EP-1866033-B1 | SUNSCREEN AEROSOL SPRAY | ENSIGN LABORATORIES PTY LTD (AU) | 2017-04-19 | — | — | EP | claimed |
| EP-1595936-B1 | COMPOSITION FOR EXTERNAL USE | VITAMIN C60 BIORES CORP (JP) | 2011-10-19 | — | — | EP | claimed |
| WO-2024139383-A1 | PREPARATION METHOD FOR COATING SOLUTION, AND DRUG BALLOON FOR NON-VASCULAR INTERVENTION AND PREPARATION METHOD THEREFOR | 微创优通医疗科技（上海）有限公司 | 2024-07-04 | — | — | WO | disclosed |
| WO-2021149827-A1 | EXTERNAL PREPARATION CONTAINING RAPAMYCIN | ノーベルファーマ株式会社 | 2021-07-29 | — | — | WO | disclosed |
| WO-2020158908-A1 | TOPICAL COMPOSITION | ロート製薬株式会社 | 2020-08-06 | — | — | WO | disclosed |
| US-20120052112-A1 | RISPERIDONE-CONTAINING TRANSDERMAL PREPARATION AND ADHESIVE PATCH USING SAME | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2012-03-01 | — | — | US | disclosed |
| WO-2012011192-A1 | TACROLIMUS-CONTAINING OIL-IN-WATER TYPE CREAMY COMPOSITION | マルホ株式会社 (JP) | 2012-01-26 | — | — | WO | disclosed |
| EP-1595936-B1 | COMPOSITION FOR EXTERNAL USE | VITAMIN C60 BIORES CORP (JP) | 2011-10-19 | — | — | EP | disclosed |
| EP-1364943-B1 | CYSTINE DERIVATIVES AND INHIBITORS FOR THE ACTIVATION OF INFLAMMATORY FACTORS | AJINOMOTO KK (JP) | 2010-10-20 | — | — | EP | disclosed |
| EP-2111860-A1 | INFLAMMATION INHIBITOR COMPRISING ZINC SALT OF ACYLAMINO ACID | Ajinomoto Co., Inc. (JP) | 2009-10-28 | — | — | EP | disclosed |
| US-20070099888-A1 | Inflammation Inhibitor Comprising Zinc Salt of Acylamino Acid | AJINOMOTO CO., INC. (JP) | 2007-05-03 | — | — | US | disclosed |
| US-20060134095-A1 | Antioxidative composition and composition for external use | VITAMIN C60 BIORESEARCH CORPORATION (JP) | 2006-06-22 | — | — | US | disclosed |
| EP-1595936-A1 | ANTIOXIDATIVE COMPOSITION AND COMPOSITION FOR EXTERNAL USE | MITSUBISHI CORPORATION (JP) | 2005-11-16 | — | — | EP | disclosed |
| US-6914075-B2 | Cystine derivative and agent for suppressing activation of inflammatory factors | AJINOMOTO CO., INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| US-20040059110-A1 | Novel cystine derivative and agent for suppressing activation of inflammatory factors | AJINOMOTO CO., INC. (JP) | 2004-03-25 | — | — | US | disclosed |
| EP-1364943-A1 | NOVEL CYSTINE DERIVATIVES AND INHIBITORS FOR THE ACTIVATION OF INFLAMMATORY FACTORS | Ajinomoto Co., Inc. (JP) | 2003-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040059110-A1 | Novel cystine derivative and agent for suppressing activation of inflammatory factors | CTH, CBS, CYSLTR1 | TDP1 2669/4885TSHR 4723/4885NPC1 4296/4885 |
| US-20060134095-A1 | Antioxidative composition and composition for external use | GPX4, GPX1, SOD1 | TDP1 3683/4885TSHR 4257/4885NPC1 1691/4885 |
| US-20070099888-A1 | Inflammation Inhibitor Comprising Zinc Salt of Acylamino Acid | NFKBIA, ZNF787, IL17A | TDP1 4464/4885TSHR 4249/4885NPC1 2051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.