Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28254252 | 0.93 | POLB (0.48) | HSD17B10ALDH1A1CYP1A2HPGDTHRB | |
| SCHEMBL27943645 | 0.85 | HSD17B10 (0.41) | HSD17B10ALDH1A1CYP1A2HPGDTHRB | |
| SCHEMBL2679230 | 0.83 | HPRT1 (0.56) | HSD17B10ALDH1A1CYP1A2HPGDTHRB | |
| SCHEMBL19862343 | 0.82 | POLB (0.42) | HSD17B10ALDH1A1CYP1A2HPGDTHRB | |
| SCHEMBL1187756 | 0.81 | POLB (0.60) | HSD17B10ALDH1A1CYP1A2HPGDTHRB | |
| SCHEMBL29487823 | 0.81 | HSD17B10 (0.72) | HSD17B10ALDH1A1CYP1A2HPGDTHRB | |
| SCHEMBL535472 | 0.81 | HSD17B10 (0.72) | HSD17B10ALDH1A1CYP1A2HPGDTHRB | |
| SCHEMBL29613365 | 0.81 | HSD17B10 (0.72) | HSD17B10ALDH1A1CYP1A2HPGDTHRB | |
| SCHEMBL1373385 | 0.80 | ALDH1A1 (0.58) | HSD17B10ALDH1A1CYP1A2HPGDTHRB | |
| SCHEMBL30065106 | 0.80 | ALDH1A1 (0.58) | HSD17B10ALDH1A1CYP1A2HPGDTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006503-B2 | Organic electroluminescence devices containing substituted benzo[C]phenanthrenes | MERCK PATENT GMBH (DE) | 2015-04-14 | — | — | US | disclosed |
| US-8710284-B2 | Materials for organic electroluminescent devices containing substituted 10-benzo[c]phenanthrenes | MERCK PATENT GMBH (DE) | 2014-04-29 | — | — | US | disclosed |
| US-20140114076-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-04-24 | — | — | US | disclosed |
| US-20110288292-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2011-11-24 | — | — | US | disclosed |
| WO-2010083869-A2 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2010-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288292-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | DDT, DDC, BMI1 | HSD17B10 1453/4885ALDH1A1 356/4885CYP1A2 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.