SCHEMBL13773302

SCHEMBL13773302

CN(C)/C=C\c1ccncc1C#N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 3/20 0.40
▸ ALDH1A1 P00352 3/20 0.35
▸ KMT2A Q03164 3/20 0.35
▸ KDM4E B2RXH2 2/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ MAPT P10636 2/20 0.35
▸ SLC22A12 Q96S37 3/20 0.35
▸ NPC1 O15118 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ NCOA3 Q9Y6Q9 1/20 0.34
▸ GAA P10253 1/20 0.33
▸ ROCK2 O75116 1/20 0.32
▸ ROCK1 Q13464 1/20 0.32
▸ CDC42BPA Q5VT25 1/20 0.32
▸ CDC42BPB Q9Y5S2 1/20 0.32
▸ PRKCQ Q04759 1/20 0.32
▸ PRKCD Q05655 1/20 0.32
▸ IRAK4 Q9NWZ3 1/20 0.31
▸ CCNT1 O60563 1/20 0.31
▸ CDK9 P50750 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3828343 1.00 HTT (0.40) HTTALDH1A1KMT2AKDM4EMEN1
SCHEMBL2982328 1.00 HTT (0.40) HTTALDH1A1KMT2AKDM4EMEN1
SCHEMBL30481365 0.87 HTT (0.40) HTTALDH1A1KMT2AKDM4EMEN1
SCHEMBL1550435 0.87 HTT (0.40) HTTALDH1A1KMT2AKDM4EMEN1
SCHEMBL1550437 0.87 HTT (0.40) HTTALDH1A1KMT2AKDM4EMEN1
SCHEMBL13415701 0.84 HTT (0.36) HTTALDH1A1KMT2AKDM4EMEN1
SCHEMBL13694776 0.77 HTT (0.43) HTTALDH1A1KMT2AKDM4EMEN1
SCHEMBL6478807 0.75 TSHR (0.42) HTTALDH1A1KMT2AKDM4EMEN1
SCHEMBL6478809 0.75 TSHR (0.42) HTTALDH1A1KMT2AKDM4EMEN1
SCHEMBL13449405 0.74 SLC22A12 (0.36) HTTALDH1A1KMT2AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1889891-B1 Luminescence device and display apparatus CANON KK (JP) 2017-11-22 — — EP disclosed
US-20150076478-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KK (JP) 2015-03-19 — — US disclosed
US-8920943-B2 Luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2014-12-30 — — US disclosed
US-8920943-B2 Luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2014-12-30 — — US disclosed
US-20090184634-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-07-23 — — US disclosed
US-7544426-B2 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2009-06-09 — — US disclosed
US-7527879-B2 Luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2009-05-05 — — US disclosed
US-20070216294-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2007-09-20 — — US disclosed
US-20070216294-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2007-09-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090184634-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS SOD1, NLRP1, LUC7L2 HTT 4648/4885ALDH1A1 120/4885KMT2A 4041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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