Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000291 | 0.85 | CYP4F2 (0.44) | TSHRALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL14770357 | 0.85 | CYP4F2 (0.37) | TSHRCYP4F2CYP4A11 | |
| SCHEMBL26420457 | 0.82 | TSHR (0.32) | TSHR | |
| SCHEMBL18068804 | 0.82 | TSHR (0.32) | TSHRCYP4F2CYP4A11 | |
| SCHEMBL17678856 | 0.80 | TSHR (0.33) | TSHR | |
| SCHEMBL16078099 | 0.79 | TSHR (0.38) | TSHR | |
| SCHEMBL29328186 | 0.79 | — | — | |
| SCHEMBL20512197 | 0.78 | TSHR (0.38) | TSHRALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL837877 | 0.78 | TSHR (0.38) | TSHRALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL8094002 | 0.78 | CYP4F2 (0.48) | TSHRALDH1A1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176866-A1 | Complexes having adjuvant activity | POLYTHERICS LIMITED (GB) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176866-A1 | Complexes having adjuvant activity | MYD88, TLR3, TLR9 | TSHR 3807/4885ALDH1A1 2687/4885CYP4F2 4772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.