Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.73 |
| ▸ | HPGD | P15428 | 9/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.73 |
| ▸ | PKM | P14618 | 3/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381685 | 0.91 | ALDH1A1 (0.73) | KDM4EALDH1A1HPGDKMT2APKM | |
| SCHEMBL5717615 | 0.82 | AR (0.73) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL11946745 | 0.81 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDKMT2APKM | |
| SCHEMBL15984893 | 0.80 | KDM4E (0.71) | KDM4EALDH1A1HPGDKMT2APKM | |
| SCHEMBL14028419 | 0.80 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDKMT2APKM | |
| SCHEMBL24198275 | 0.80 | ALDH1A1 (0.74) | KDM4EALDH1A1HPGDKMT2APKM | |
| SCHEMBL15499732 | 0.80 | ALDH1A1 (0.79) | KDM4EALDH1A1HPGDKMT2APKM | |
| SCHEMBL14756052 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1HPGDKMT2APKM | |
| SCHEMBL11390799 | 0.79 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDKMT2APKM | |
| SCHEMBL14027239 | 0.79 | KDM4E (0.63) | KDM4EALDH1A1HPGDKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | PRKCH, AIP, PRKCE | KDM4E 2954/4885ALDH1A1 4689/4885HPGD 3252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.