Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.79 |
| ▸ | PKM | P14618 | 3/20 | 0.79 |
| ▸ | MEN1 | O00255 | 3/20 | 0.79 |
| ▸ | POLB | P06746 | 2/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.79 |
| ▸ | HPGD | P15428 | 11/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24198275 | 0.89 | ALDH1A1 (0.74) | ALDH1A1KMT2APKMMEN1POLB | |
| SCHEMBL13381685 | 0.88 | ALDH1A1 (0.73) | ALDH1A1KMT2APKMMEN1POLB | |
| SCHEMBL11316690 | 0.85 | AR (0.74) | ALDH1A1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL7000666 | 0.81 | ALDH1A1 (0.63) | ALDH1A1KMT2APKMMEN1POLB | |
| SCHEMBL6031499 | 0.80 | CYP2D6 (0.76) | ALDH1A1KMT2APKMMEN1POLB | |
| SCHEMBL13779255 | 0.80 | KDM4E (0.73) | ALDH1A1KMT2APKMMEN1POLB | |
| SCHEMBL7917198 | 0.79 | ALDH1A1 (0.67) | ALDH1A1KMT2APKMMEN1POLB | |
| SCHEMBL15944529 | 0.79 | KDM4E (0.69) | ALDH1A1KMT2APKMMEN1POLB | |
| SCHEMBL11390831 | 0.78 | ALDH1A1 (0.73) | ALDH1A1KMT2APKMMEN1POLB | |
| SCHEMBL16607324 | 0.77 | AGER (0.67) | ALDH1A1KMT2APKMMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140066537-A1 | ORGANIC COMPOSITIONS FOR REPEATEDLY ADJUSTABLE OPTICAL ELEMENTS AND SUCH ELEMENTS | UNIVERSITE DE LIEGE (BE) | 2014-03-06 | — | — | US | disclosed |