Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3899672 | 0.81 | NPC1 (0.75) | RAB9ANPC1KDM4EALDH1A1MEN1 | |
| SCHEMBL18313849 | 0.78 | KDM4E (0.60) | RAB9ANPC1KDM4ENR2F2ALDH1A1 | |
| SCHEMBL3886114 | 0.74 | SMN1; SMN2 (0.54) | RAB9ANPC1KDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL14119393 | 0.73 | SMN1; SMN2 (0.56) | RAB9ANPC1KDM4EALDH1A1MEN1 | |
| Bromide SCHEMBL9517907 | 0.73 | NPC1 (0.55) | RAB9ANPC1KDM4EALDH1A1MEN1 | |
| SCHEMBL20042582 | 0.73 | SMN1; SMN2 (0.56) | RAB9ANPC1KDM4ENR2F2ALDH1A1 | |
| SCHEMBL29520514 | 0.73 | KDM4E (0.97) | RAB9ANPC1KDM4ENR2F2ALDH1A1 | |
| SCHEMBL3006822 | 0.71 | KMT2A (0.52) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL7122888 | 0.70 | NPC1 (0.55) | RAB9ANPC1KDM4EALDH1A1MEN1 | |
| SCHEMBL17830465 | 0.69 | MAPT (0.53) | RAB9ANPC1KDM4ENR2F2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | PRKCH, AIP, PRKCE | RAB9A 959/4885NPC1 1716/4885KDM4E 2954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.