Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886114 | 0.98 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E | |
| Bromide SCHEMBL9517907 | 0.96 | NPC1 (0.55) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL7122888 | 0.81 | NPC1 (0.55) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL3273982 | 0.74 | KMT2A (0.38) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL13779317 | 0.73 | RAB9A (0.65) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL24163129 | 0.65 | CSNK2A2 (0.38) | ALDH1A1KMT2AMEN1KDM4EPOLB | |
| SCHEMBL3889066 | 0.64 | INMT (0.44) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL6950367 | 0.64 | ALDH1A1 (0.36) | ALDH1A1KMT2AMEN1KDM4EPOLB | |
| Bromide SCHEMBL1668833 | 0.63 | ALDH1A1 (0.35) | ALDH1A1KMT2AMEN1KDM4ENPC1 | |
| SCHEMBL3719707 | 0.63 | KDM4E (0.53) | ALDH1A1KMT2AMEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12472543-B2 | Waste disposal system and waste receiver for receiving and disposing of pharmaceutical waste material | STRYKER CORPORATION (US) | 2025-11-18 | — | — | US | disclosed |
| US-12434282-B2 | Pharmaceutical waste system | STRYKER CORPORATION (US) | 2025-10-07 | — | — | US | disclosed |
| US-20250268679-A1 | Waster Receiver For Receiving A Pharmaceutical Waste Material | STRYKER CORPORATION (US) | 2025-08-28 | — | — | US | disclosed |
| US-12318823-B2 | Waste receiver for receiving a pharmaceutical waste material | STRYKER CORPORATION (US) | 2025-06-03 | — | — | US | disclosed |
| US-20250144680-A1 | Pharmaceutical Waste Disposal Assembly | STRYKER CORPORATION (US) | 2025-05-08 | — | — | US | disclosed |
| EP-3902638-B1 | METHOD OF DISPOSING OF WASTE RECEIVER AND WASTE RECEIVER FOR PHARMACEUTICAL WASTE | STRYKER CORP (US) | 2025-02-26 | — | — | EP | disclosed |
| US-12194516-B2 | Pharmaceutical waste disposal assembly | STRYKER CORPORATION (US) | 2025-01-14 | — | — | US | disclosed |
| US-20240359222-A1 | Waste Receiver For Receiving A Pharmaceutical Waste Material | STRYKER CORPORATION (US) | 2024-10-31 | — | — | US | disclosed |
| US-12064797-B2 | Method of disposing of waste receiver, waste receiver for pharmaceutical waste and method of assembling the waste receiver | STRYKER CORPORATION (US) | 2024-08-20 | — | — | US | disclosed |
| US-20240066574-A1 | Waste Disposal System And Waste Receiver For Receiving And Disposing Of Pharmaceutical Waste Material | STRYKER CORPORATION (US) | 2024-02-29 | — | — | US | disclosed |
| US-20190126331-A1 | Waste Disposal System And Waste Receiver For Receiving And Disposing Of Pharmaceutical Waste Material | STRYKER CORPORATION (US) | 2019-05-02 | — | — | US | disclosed |
| US-20190084018-A1 | Pharmaceutical Waste Disposal Assembly | STRYKER CORPORATION (US) | 2019-03-21 | — | — | US | disclosed |
| WO-2019006346-A1 | WASTE DISPSAL SYSTEM AND WASTE RECEIVER FOR RECEIVING AND DISPOSING OF PHARMACEUTICAL WASTE MATERIAL | STRYKER CORPORATION (US) | 2019-01-03 | — | — | WO | disclosed |
| US-10086416-B2 | Pharmaceutical waste disposal assembly | STRYKER CORPORATION (US) | 2018-10-02 | — | — | US | disclosed |
| WO-2018049139-A2 | A PHARMACEUTICAL WASTE SYSTEM | STRYKER CORPORATION (US) | 2018-03-15 | — | — | WO | disclosed |
| US-20160325322-A1 | PHARMACEUTICAL WASTE DISPOSAL ASSEMBLY | STRYKER CORPORATION | 2016-11-10 | — | — | US | disclosed |
| US-9456954-B2 | Pharmaceutical waste disposal assembly | CACTUS, LLC (US) | 2016-10-04 | — | — | US | disclosed |
| US-9044377-B2 | Pharmaceutical waste disposal assembly | CACTUS, LLC (US) | 2015-06-02 | — | — | US | disclosed |
| US-20140190845-A1 | PHARMACEUTICAL WASTE DISPOSAL ASSEMBLY | CACTUS, LLC (US) | 2014-07-10 | — | — | US | disclosed |
| US-20120305132-A1 | PHARMACEUTICAL WASTE DISPOSAL ASSEMBLY | CACTUS, LLC. | 2012-12-06 | — | — | US | disclosed |