Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.97 |
| ▸ | RAB9A | P51151 | 3/20 | 0.97 |
| ▸ | NPC1 | O15118 | 1/20 | 0.97 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.97 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18313849 | 0.76 | KDM4E (0.60) | KDM4ERAB9ANPC1NR2F2SMN1; SMN2 | |
| SCHEMBL10247417 | 0.75 | CYP19A1 (0.68) | KDM4ERAB9ANPC1NR2F2L3MBTL1 | |
| SCHEMBL28115922 | 0.75 | KDM4E (0.57) | KDM4ERAB9ANPC1NR2F2SMN1; SMN2 | |
| SCHEMBL7896851 | 0.74 | KDM4E (0.57) | KDM4ERAB9ANPC1NR2F2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL412291 | 0.74 | CYP19A1 (0.67) | KDM4ERAB9ANPC1NR2F2L3MBTL1 | |
| SCHEMBL13779317 | 0.73 | RAB9A (0.65) | KDM4ERAB9ANPC1NR2F2SMN1; SMN2 | |
| SCHEMBL13267956 | 0.73 | NPC1 (0.54) | KDM4ERAB9ANPC1NR2F2SMN1; SMN2 | |
| SCHEMBL11453430 | 0.73 | SMN1; SMN2 (0.67) | KDM4ERAB9ANPC1NR2F2SMN1; SMN2 | |
| SCHEMBL20042582 | 0.71 | SMN1; SMN2 (0.56) | KDM4ERAB9ANPC1NR2F2SMN1; SMN2 | |
| Bromide SCHEMBL6074979 | 0.71 | MEN1 (0.84) | KDM4ERAB9ANPC1NR2F2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220249436-A1 | Small Molecule Agonists and Antagonists of NR2F6 Activity in Humans | KCL THERAPEUTICS, INC (US) | 2022-08-11 | — | — | US | disclosed |
| US-11377442-B2 | Small molecule agonists and antagonists of NR2F6 activity | Zander Biologics, Inc (US) | 2022-07-05 | — | — | US | disclosed |
| US-11324719-B2 | Small molecule agonists and antagonists of NR2F6 activity in humans | KCL THERAPEUTICS, INC. (US) | 2022-05-10 | — | — | US | disclosed |
| US-11241427-B2 | Small molecule modulators of NR2F6 activity | KCL THERAPEUTICS, INC. (US) | 2022-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11241427-B2 | Small molecule modulators of NR2F6 activity | NR2F2, NR2E3, NR2C2 | KDM4E 1747/4885RAB9A 4128/4885NPC1 4046/4885 |
| US-20220249436-A1 | Small Molecule Agonists and Antagonists of NR2F6 Activity in Humans | NR4A2, NR2C2, NR0B2 | KDM4E 3440/4885RAB9A 3645/4885NPC1 1496/4885 |
| US-11324719-B2 | Small molecule agonists and antagonists of NR2F6 activity in humans | NR4A2, NR2C2, NR0B2 | KDM4E 3440/4885RAB9A 3645/4885NPC1 1496/4885 |
| US-11377442-B2 | Small molecule agonists and antagonists of NR2F6 activity | NR4A2, NR2C2, NR2F2 | KDM4E 3502/4885RAB9A 3762/4885NPC1 1681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.