SCHEMBL13779474

SCHEMBL13779474

CC(=O)Oc1ccc(C2(c3ccc(OC(=O)c4ccccc4)cc3)CCCCC2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.53
MAPT P10636 5/20 0.51
TDP1 Q9NUW8 3/20 0.51
KMT2A Q03164 9/20 0.50
MEN1 O00255 4/20 0.50
SLC6A2 P23975 2/20 0.50
SLC6A3 Q01959 2/20 0.50
SLC6A4 P31645 1/20 0.50
ALDH1A1 P00352 3/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
PKM P14618 1/20 0.48
PARP10 Q53GL7 1/20 0.47
ADORA3 P0DMS8 2/20 0.46
ESR1 P03372 1/20 0.43
PGR P06401 1/20 0.43
CHRM2 P08172 1/20 0.43
AR P10275 1/20 0.43
CHRM1 P11229 1/20 0.43
HSP90AA1 P07900 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9561801 0.93 KMT2A (0.56) MAPTTDP1KMT2AMEN1SLC6A2
SCHEMBL1256640 0.90 ELANE (0.51) ELANEMAPTKMT2AMEN1SLC6A2
SCHEMBL2718813 0.89 KMT2A (0.50) MAPTTDP1KMT2AMEN1SLC6A2
SCHEMBL14580087 0.88 LMNA (0.50) MAPTTDP1KMT2AMEN1SLC6A2
SCHEMBL12337416 0.88 ESR1 (0.56) MAPTTDP1KMT2AMEN1SLC6A2
SCHEMBL10907042 0.87 ADORA3 (0.52) ELANEMAPTKMT2AMEN1SLC6A2
SCHEMBL12015967 0.86 ADORA3 (0.55) ELANEMAPTTDP1KMT2AMEN1
SCHEMBL18780368 0.84 KMT2A (0.48) MAPTTDP1KMT2AMEN1SLC6A2
SCHEMBL17792236 0.83 MAPT (0.65) MAPTTDP1KMT2AMEN1SLC6A2
SCHEMBL16705193 0.82 ELANE (0.75) ELANEMAPTTDP1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7556902-B2 Aromatic polyester resin, and electrophotographic photoconductor and image forming apparatus using thereof RICOH COMPANY, LTD. (JP) 2009-07-07 US disclosed