Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 13/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13779645 | 0.96 | CYP17A1 (0.42) | TSHRCYP17A1CYP19A1EPHX2POLB | |
| SCHEMBL2740753 | 0.91 | CYP17A1 (0.43) | TSHRCYP17A1CYP19A1EPHX2THRB | |
| SCHEMBL10027335 | 0.88 | CYP17A1 (0.42) | TSHRCYP17A1CYP19A1EPHX2POLB | |
| SCHEMBL214191 | 0.82 | CYP17A1 (0.42) | TSHRCYP17A1CYP19A1THRBALDH1A1 | |
| SCHEMBL12704685 | 0.82 | TSHR (0.39) | TSHREPHX2POLBAPEX1HTT | |
| SCHEMBL950092 | 0.82 | THRB (0.44) | TSHRCYP17A1CYP19A1THRBALDH1A1 | |
| SCHEMBL10027336 | 0.81 | THRB (0.41) | TSHRCYP17A1CYP19A1POLBAPEX1 | |
| SCHEMBL212781 | 0.80 | CYP17A1 (0.41) | TSHRCYP17A1CYP19A1EPHX2THRB | |
| SCHEMBL10136378 | 0.80 | THRB (0.35) | TSHRCYP17A1CYP19A1EPHX2POLB | |
| SCHEMBL10136410 | 0.79 | TSHR (0.36) | TSHREPHX2POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7556908-B2 | Chemically amplified positive resist composition, (meth)acrylate derivative and a process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-07-07 | — | — | US | disclosed |