Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13488596 | 0.82 | NPSR1 (0.66) | HPGDNPSR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6960896 | 0.80 | HPGD (0.44) | HPGDNPSR1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL15803898 | 0.78 | NPSR1 (0.47) | HPGDNPSR1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL11652842 | 0.78 | HPGD (0.72) | HPGDALDH1A1MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL10142193 | 0.75 | POLB (0.32) | HPGDNPSR1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8145766 | 0.73 | CYP1A2 (0.67) | HPGDNPSR1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL11584471 | 0.73 | ALDH1A1 (0.52) | HPGDNPSR1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL6968502 | 0.73 | CYP1A2 (0.43) | HPGDNPSR1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL15806516 | 0.72 | HPGD (0.54) | HPGDALDH1A1MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL14090615 | 0.72 | KMT2A (0.33) | HPGDNPSR1ALDH1A1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090177267-A1 | Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2009-07-09 | — | — | US | disclosed |