Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR3A | P46098 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1380554 | 0.89 | KEAP1 (0.56) | HTR6HTR1AHTR3AMAPTMEN1 | |
| SCHEMBL1377353 | 0.88 | HTR6 (0.47) | HTR6HTR1AHTR3AMAPTMEN1 | |
| SCHEMBL1380560 | 0.85 | HTR6 (0.53) | HTR6HTR1AHTR3AMAPTNCF1 | |
| SCHEMBL3624092 | 0.85 | KEAP1 (0.63) | HTR6HTR1AHTR3AMAPTMEN1 | |
| SCHEMBL1379529 | 0.84 | HTR6 (0.51) | HTR6HTR1AHTR3AMAPTKEAP1 | |
| SCHEMBL3623223 | 0.81 | KEAP1 (0.59) | HTR6MAPTMEN1KMT2AKEAP1 | |
| SCHEMBL1381586 | 0.81 | HTR6 (0.56) | HTR6MAPTMEN1KMT2ANCF1 | |
| SCHEMBL1380651 | 0.81 | HTR6 (0.60) | HTR6HTR1ANCF1 | |
| SCHEMBL1380982 | 0.81 | HTR6 (0.57) | HTR6HTR1AHTR3AMAPTNCF1 | |
| Hydrochloric Acid SCHEMBL5550931 | 0.80 | HTR6 (0.59) | HTR6HTR1ANCF1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4731114-B2 | — | — | 2011-07-20 | — | — | JP | claimed |