Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | AKT2 | P31751 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.49 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.49 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13784103 | 0.96 | ESR1 (0.51) | ESR1ESR2AKT1AKT2GRIA1 | |
| SCHEMBL19374106 | 0.91 | ESR1 (0.67) | ESR1ESR2AKT1AKT2GRIA1 | |
| SCHEMBL13784050 | 0.90 | ESR1 (0.48) | ESR1ESR2AKT1AKT2GRIA1 | |
| SCHEMBL26017755 | 0.90 | ESR2 (0.60) | ESR1ESR2AKT1AKT2GRIA1 | |
| SCHEMBL13784124 | 0.90 | ESR2 (0.68) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL31037944 | 0.90 | ESR1 (0.53) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL13784162 | 0.89 | ESR1 (0.46) | ESR1ESR2AKT1AKT2GRIA1 | |
| SCHEMBL15064151 | 0.88 | ESR1 (0.58) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL20776053 | 0.88 | ESR1 (0.59) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL20776036 | 0.88 | ESR1 (0.59) | ESR1ESR2GRIA1CACNG8CACNG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815412-B2 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic appliance using the quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-08-26 | — | — | US | disclosed |
| US-8815412-B2 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic appliance using the quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-08-26 | — | — | US | disclosed |
| US-20090184633-A1 | Quinoxaline Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Appliance Using the Quinoxaline Derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2009-07-23 | — | — | US | disclosed |
| US-20090184633-A1 | Quinoxaline Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Appliance Using the Quinoxaline Derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090184633-A1 | Quinoxaline Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Appliance Using the Quinoxaline Derivative | H1-0, NQO2, GDI1 | ESR1 1434/4885ESR2 2914/4885AKT1 3978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.