SCHEMBL15064151

SCHEMBL15064151

CC(C)(C)c1ccc(-c2nc3ccccc3n2-c2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.58
ESR2 Q92731 1/20 0.58
MAPK1 P28482 2/20 0.55
HTT P42858 1/20 0.55
GRIA1 P42261 1/20 0.53
CACNG8 Q8WXS5 1/20 0.53
CACNG2 Q9Y698 1/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 2/20 0.53
NPSR1 Q6W5P4 1/20 0.53
PTGS2 P35354 1/20 0.48
RECQL P46063 1/20 0.48
PIN1 Q13526 2/20 0.47
ADORA2A P29274 1/20 0.47
PRKACA P17612 1/20 0.47
RPS6KB1 P23443 1/20 0.47
GSK3B P49841 1/20 0.47
ROCK1 Q13464 1/20 0.47
KDM4E B2RXH2 2/20 0.46
SLC22A12 Q96S37 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26017755 0.95 ESR2 (0.60) ESR1ESR2MAPK1HTTGRIA1
SCHEMBL20776033 0.95 ESR1 (0.53) ESR1ESR2MAPK1HTTGRIA1
SCHEMBL19374106 0.94 ESR1 (0.67) ESR1ESR2MAPK1HTTGRIA1
SCHEMBL25752070 0.92 ALDH1A1 (0.53) ESR1ESR2MAPK1HTTGRIA1
SCHEMBL13784103 0.92 ESR1 (0.51) ESR1ESR2MAPK1HTTGRIA1
SCHEMBL20776053 0.91 ESR1 (0.59) ESR1ESR2MAPK1HTTGRIA1
SCHEMBL20776036 0.91 ESR1 (0.59) ESR1ESR2MAPK1HTTGRIA1
SCHEMBL14278941 0.90 ESR1 (0.60) ESR1ESR2MAPK1HTTGRIA1
SCHEMBL28161173 0.89 ESR2 (0.53) ESR1ESR2MAPK1HTTGRIA1
SCHEMBL16435316 0.88 ESR1 (0.53) ESR1ESR2MAPK1HTTGRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11832510-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-11713333-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-08-01 US disclosed
US-20220220084-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2022-07-14 US disclosed
US-20220216426-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2022-07-07 US disclosed
US-11050026-B2 Spiro compound and organic light-emitting element comprising same LG CHEM, LTD. 2021-06-29 US disclosed
US-10981876-B2 Spiro compound and organic light emitting element comprising same LG CHEM, LTD. 2021-04-20 US disclosed
US-10968230-B2 Spiro-structured compound and organic electronic device comprising same LG CHEM, LTD. 2021-04-06 US disclosed
US-10964895-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-03-30 US disclosed
US-20200411775-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-12-31 US disclosed
US-10734590-B2 Heterocyclic compound and organic light-emitting element using same LG CHEM, LTD. (KR) 2020-08-04 US disclosed
US-20160233432-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME LG CHEM, LTD. (KR) 2016-08-11 US disclosed
US-20160149139-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-26 US disclosed
US-9166175-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-10-20 US disclosed
US-9112159-B2 Bipolar hosts for light emitting devices NITTO DENKO CORPORATION (JP) 2015-08-18 US disclosed
US-20140163237-A1 BIPOLAR HOSTS FOR LIGHT EMITTING DEVICES Nitto Denko Corportion (JP) 2014-06-12 US disclosed
US-20140145149-A1 Organic Luminescent Compound With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-29 US disclosed
US-20140145151-A1 Organic Electroluminescent Device With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-29 US disclosed
US-20130172570-A1 METHOD OF MAKING BENZAZOLES US GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2013-07-04 US disclosed
US-20130172570-A1 METHOD OF MAKING BENZAZOLES US GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2013-07-04 US disclosed
US-20130172570-A1 METHOD OF MAKING BENZAZOLES US GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2013-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11713333-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound ORC3, LAGE3, ORMDL3 ESR1 750/4885ESR2 2382/4885MAPK1 4744/4885
US-11832510-B2 Organic electroluminescent materials and devices OSBP, OCIAD2, OCIAD1 ESR1 326/4885ESR2 229/4885MAPK1 4132/4885
US-10734590-B2 Heterocyclic compound and organic light-emitting element using same CRY1, CRY2, NR2E3 ESR1 19/4885ESR2 300/4885MAPK1 3724/4885
US-20140145149-A1 Organic Luminescent Compound With Delayed Fluorescence OCIAD1, OCIAD2, MLYCD ESR1 1440/4885ESR2 2179/4885MAPK1 4294/4885
US-10968230-B2 Spiro-structured compound and organic electronic device comprising same ESR1, OR10J3, ERG ESR1 1/4885ESR2 7/4885MAPK1 3296/4885
US-10964895-B2 Organic electroluminescent materials and devices CCND1, CCND2, EED ESR1 96/4885ESR2 228/4885MAPK1 1332/4885
US-10981876-B2 Spiro compound and organic light emitting element comprising same RER1, RIF1, CRY1 ESR1 8/4885ESR2 23/4885MAPK1 900/4885
US-20130172570-A1 METHOD OF MAKING BENZAZOLES NBAS, CBR3, CBR1 ESR1 3457/4885ESR2 3322/4885MAPK1 3955/4885
US-20220220084-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC APPARATUS EXOC4, CYBA, SCO2 ESR1 96/4885ESR2 314/4885MAPK1 3337/4885
US-20220216426-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS NCL, DNMT3A, NUDT1 ESR1 399/4885ESR2 1328/4885MAPK1 3390/4885
US-11050026-B2 Spiro compound and organic light-emitting element comprising same NR2E3, CRY1, ERG ESR1 5/4885ESR2 18/4885MAPK1 3606/4885
US-20200411775-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD2, OCIAD1 ESR1 326/4885ESR2 229/4885MAPK1 4132/4885
US-20160233432-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME CRY1, CRY2, NR2E3 ESR1 19/4885ESR2 300/4885MAPK1 3724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.