Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.61 |
| ▸ | CTSL | P07711 | 15/20 | 0.61 |
| ▸ | CTSS | P25774 | 15/20 | 0.61 |
| ▸ | CTSB | P07858 | 3/20 | 0.49 |
| ▸ | CTSV | O60911 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4316121 | 0.94 | CTSK (0.61) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4316126 | 0.94 | CTSK (0.61) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4321792 | 0.93 | CTSK (0.59) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4321788 | 0.93 | CTSK (0.59) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL13784234 | 0.79 | CTSK (0.66) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6577836 | 0.79 | CTSK (0.64) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4557501 | 0.78 | CTSK (0.47) | CTSKCTSLCTSSMMP1ADAM17 | |
| SCHEMBL4557499 | 0.78 | CTSK (0.47) | CTSKCTSLCTSSMMP1ADAM17 | |
| SCHEMBL7478030 | 0.76 | CTSK (1.00) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6842102 | 0.75 | CTSK (0.43) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563784-B2 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-21 | — | — | US | disclosed |